Why to say platelet is one of the most important blood analyzer test project?

Why to say platelet is one of the most important blood analyzer test project? The following appeared blood analyzer, blood analyzer are refers to the blood analyzer, belong to the same kind of medical apparatus and instruments.

Blood analyzer platelet area has four parameters: platelet (PLT), platelet press (PCT), mean platelet volume (MPV) and platelet volume distribution width (PDW) report on the PLT height is obvious, but in some diseases PLT and platelet volume closely, analysis the relationship between the two very important PLT decrease and MP V increases, in no clinical symptoms and signs of acute myocarditis artery, cardiac hypertrophic osteoarthropathy, extracorporeal circulation when immune thrombocytopenic purple paralysis, diabetes and coronary heart disease patients increased PLT and MPV normal, in myeloid proliferative diseases, reactive platelet hyperplasia and large area inflammatory reaction, infection, cancer and other relevant PLT and MPV decreased, in dysplastic anemia, HIV/AIDS, spleen function hyperfunction, bone marrow fiber, tumor infiltration, pure megakaryocyte dysplasia, aplastic anemia, sepsis, megaloblastic anemia PLT and MPV are increased, in reactive thrombocytosis and iron deficiency anemia MPV value increase, PLT normal, in chronic myelogenous leukemia, myelofibrosis, splenectomy, leukemia chemotherapy patients MPV value drop before PLT decline when primary thrombocytopenia MPV value maximum, when alleviate PLT when rise, MPV is reduced, PLT of normal, MPV also normal.

Abnormal platelet platelet and red blood cells in the same channels in measurement, both in volume has obvious difference, blood analyzer set a specific stop value, will be higher than stop value as the red blood cells, and platelets but for red blood cell group the small red blood cells or cell debris can fall in platelet stop value inside, huge platelet or gathered platelet can be mistaken for red blood cells, these all can from platelet histogram reflected in additional, chyle particles, cold globulin particles and erythrocyte condensing set and so on also can disturb the PLT results, but platelet histogram no obvious change.

Small platelets in the blood analyzer the curve peak right ci left, in less than 20 fl at some point and x axis coincidence, MPV value significantly reduce if PLT decrease, visible at the AIDS virus infection and spleen hyperfunction etc; If PLT normal, seen in chronic aplastic anemia; If PLT increases, seen in reactive thrombocytosis disorder.

Big platelets in the blood cell analyzer the curve peak right right shift, in more than 30 fI at some point and x axis coincidence, MIPV value significantly higher if the platelet count reduction, seen in idiopathic thrombocytopenic purple paralysis and extracorporeal circulation; If the platelet count increases, in after splenectomy if platelet count is normal, seen in chronic myelogenous leukemia, bone marrow fibrosis and other uneven size platelet, mainly platelet histogram display curve peak right shift and bottom up.

Gather the platelet curve peak become low, if to less than 20 platelet aggregation is given priority to, curve peak right up in tow caudate, not with x axis coincidence, If to more than 20 platelet aggregation is given priority to, the curve peak become low, flat, and the right side up is not obvious at this time, in the leucocyte histogram 35 fL place has a small peak, specimen collection is improper or ethylenediamine tetraacetic acid dependence platelet aggregation, etc.

To sum up, although blood analyzer for disease diagnosis, differential diagnosis and curative effect observation offers a number of important basis, but still can't replace microscopy, only as microscopy screening, and should combine blood analyzer of other parameters comprehensive analysis, meet instrument issued a warning signal, must, in accordance with international hematology review panel recommended article 41 review rules inspected.

Article : From Perlong medical (http://www.pl999.net/)
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