2012年2月29日星期三

The testing analysis of Cardiac troponin

   Cardiac Troponin is from three different genes and the composition:
    Myocardial for troponin T (cTnT)-myosin combined with the unit
    Myocardial cTnI (cTnI)-inhibit the unit
    Muscle calcium protein C (TnC)-calcium combined with the unit

     (1) Because cTnI molecules in the blood is easily in the first end from C protease (amino acid 1 ~ 30), and again from N end (amino acid 110 ~ 210) degradation; CTnI containing two serine surface and two homocysteine residual base, the base is in the body ser protein kinase A phosphorylation, make cTnI molecular configuration change, can affect the antibodies that bind to; When 50% of the blood circulation AMI cTnI is phosphorylated form. Cysteine remnants and easy oxidation or reduction, this will also change cTnI molecular configurations. Only in the central WenDingOu preparation cTnI molecules antigen decided to cluster, and at the same time without regard to the above factors monoclonal antibodies to the heart of the release to the determination of molecules on cTnI. Kit for different antigen cTnI cluster of antibodies to identify different sites, some antibody combine part just the unstable or configuration change area, detection in the form of the blood cTnI is different also, so different from a range of kit reference, the standardization is the current cTnI presses for solution of the big problem. Select a table for stability of monoclonal antibodies reagents can get stability test results.

    (2) In the diagnosis of AMI, cTnT cTnI and the same value

    (3) Serious hemolysis will effect on the determination results, but slight hemolysis or blood fat to has no effect on the results. Some cTnI kit may affected by people of the opposite sex, a rat antibody antibodies and the influence of rheumatoid factor.

   (4) The results of analysis of plasma and serum differences, must pay attention to the requirements of the sample kit.

XFA6000 Intelligent Auto Hematology Analyzer

As you know, Hematology Analyzer is an in-vitro diagnostic equipment which is applied to quantitative analysis of blood cells of clinical and laboratory. As a medical equipment manufacturer, We perlong Medical succeed to present the XFA6000 series. Here, let me introduce our most popular type XFA6000 Intelligent Auto Hematology Analyzer.

   Firstly, our
hematology analyzers are mainly used to detect the parameters of the series of red blood cells(RBC) and hemoglobin(HGB) platelet(PLT)and leukocyte(WBC) in the blood. Then doctors can diagnose disease according to the test result of these items.

    Then let me introduce some of its main technical parameters. The sample volume is 13ul of whole blood or 20ul of twig blood. Its LCD display is 8 inches and can be operated by touching the screen, so it is very convenient.

    The test speed can reach 60 samples per hour and continuous work time is more than 8 hours. The interfaces include RS232, LAN112 USB adapter, PS2 keyboard, computer mouse, printer interface, audio.

   The last is the most important, as you know, this type is the newest product, so it has some outstanding features. It adopts electrical impedance principle and it is mainly used for the quantitative measurement of the blood in the 19 parameters and 3 histograms, so we usually call it 22 items or three classifications. Secondly, it uses screw transmission technology, so it can insure the accuracy and efficiency of the test result. Thirdly, the machine has intelligent testing procedure, such as intelligent barcode scanning, automatic sample bleeding, voice announce and automatic warning, online update supporting etc. It can save 20,000 test result and the date can be searched by date ID, SN. It has a built-in thermal printer. Also it can set up and edit the parameters of male, female, children and newborn.

    Follow the principle "Cherish your life and care about your health",we can give you more and do the best!     

Perlong medical equipment nets analyzes creatine kinase isozyme clinical significance

Creatine kinase isozyme divided into: CK-BB, CK-MB, CK-MM the three isozymes. The following is perlong medical equipment nets analyzes creatine kinase isozyme clinical significance:
      A, CK-BB (CK1) with mild or moderate brain-damaged patients serum CK-BB evidently higher than those of control value, serum CK-BB on brain damage of the size and the scope of the high and low mortality rate consistent; In cerebrovascular accident and brain surgery, serum CK-BB may also rise. Premature newborn suffocation, if CSFCK-BB rise, more substantial damage occurred brain tissue tip; If CK-BB more than CSF-CF total active 15, is vulnerable to cerebral palsy, intelligence development light obstacles and serious complications.
      Second, CK-MB (CK2) serum CK-MB determination of the most important significance lies in the diagnosis of acute myocardial infarction. Acute myocardial infarction chest pain after a 4 ~ 6 hours, the patient serum CK-MB total activity before beginning to rise, 12 ~ 36 hours to spike; More than 72 hours of normal.
      Three, CK-MM (CK3) skeletal muscle almost contains only CK-MM, myocardial except CK-MB outside, also the main containing this type isozyme. CK-MM is healthy adults serum CK the main ingredients.
      Four, the giant CK (M-CK) adult serum M-CK-I though specific diseases and nothing, but the because of lack of oxygen happened premature suffocation of cerebral palsy or epilepsy for newborn, the serum M-CK-I was sure nerve damage early indicator, the brain is long-term anoxic, release CK-BB in the blood and the result of the Ig polymerization, also have the potential to judge the value of curative effect.

2012年2月28日星期二

Urine Chemistry analyzer validation patients and glycemic load the uric acid

Experts in through the with blood sugar and high blood pressure patients uric acid test research shows that uric acid in patients with high blood pressure is normal sugar and 1 hour after glycemic load significant correlation.
      An oral glucose tolerance test (OGTT) 1 hour quartile blood sugar 155 mg/dl can determine the risk of type 2 diabetes and the clinical organ damage NGT of subjects. Even so, still be classified as low NGT individuals threatened the crowd. High uric acid with high blood pressure, blood insulin resistance and diabetes and several kinds of cardiovascular disease risk related. But it is still not clear uric acid in hypertensive NGT individuals can affect blood glucose after 1 hour load. The study participants included 955 patients with hypertension outpatient service of OGTT routine. Laboratory index is to evaluate and estimated the estimated glomerular filtration rate.
      The results showed that uric acid in the whole crowd for 1 hour after the main prediction blood sugar load factors; In a separate model, NGT quartile 155 mg/dl subjects, glucose tolerance and damaged in patients with type 2 diabetes accounted for 26.0% of the variation, 25.3%, 13.5% and 13.5%.

Microplate enzymes : application of immune determination

Enzyme which is of microplate reader were used for drug and immune mainly small molecules detection ELISA is much more widely used, and it can be used to test the project includes the following respects.

1.Pathogen and its antibodies are widely used in the diagnosis of infectious virus hepatitis virus rubella virus herpes virus rotavirus, etc.; Mycobacterium tuberculosis bacteria, such as the streptococcus helicobacter pylori and brinell coli, etc.; Parasites such as day 2 amebic plasmodium falciparum, etc.

2.Protein molecule components of immunoglobulin tumor markers (such as a child protein carcinoma antigen embryo prostate specific antigen, etc) all sorts of plasma protein isozymes (such as creatine kinase CK-MB) hormone (such as hCG FSH TSH).

The peptide hormones such as T3 T4 estrogen cortisol, etc

4. Drugs and drugs such as digoxin benzene benzodiazepines gentamycin morphine and so on

Enzyme immunoassays are highly sensitivity and specificity, almost all of the soluble antigen antibody system to detect it can all be the smallest testable value can reach ng pg level and even ria than analysis, the enzyme is the advantage of immune determination mark reagents is stable, and there is no harm radioactive, therefore, the application of the enzyme immunoassays changes with each new day, the enzyme immune new method for the determination of the new technology development but enzyme immunoassays in medical inspection in popular due to commodity kit and automatic or semi-automatic testing instrument the appearance of the enzyme were immune complex step, reagent preparation is only with difficulty to meet the requirements of reagent and standardized operation, can obtain satisfactory results

Commodity ELISA kit should include bag was good solid phase carrier enzyme combined substrates and twist and other advanced kit not only provide all reagent ingredients, and all are made into reagents application liquid, and in all kinds of reagent to add pigment, make present different color ELISA procedures, reagents used is much also, this is a convenient operation and non-ferrous reagent to reduce operating error ELISA all except to quantitatively measure instrument need in the excellent instrument (special called ELISA read the instrument) outside, washing board is also extremely useful washing machine using not only save time save work, but also to standardized operation, to small and medium-sized laboratory is practical and accessible but should pay attention to in using
microplate washer before, should be first to wash the performance of the machine to check, confirm the hole cleaning effect is thoroughly, and repeat it well.

Semi-automatic and
automation ELISA analyzer also is mature, and in the large and medium-sized clinical inspection laboratory automation ELISA analyzer has application has an open system (open system) and closed system (close system) two classes of the former is applicable to all 96 hole plate ELISA determination; The latter only and supporting the use of specific reagents
Immune filtration test and immune chromatography test is a simple fast single testing results of many advantages, such as no equipments, instruments, reagent stable, so much of this kind of test for emergency inspection not accurate quantitative, so mainly limited to test the normal body fluids not the substance (such as the diagnosis of infectious diseases or antigen antibody), and normal and very low content in a special case abnormal rising material (such as hCG) currently clinical inspection has carried out a project hCG of HCV and HIV, HBsAg etc, new projects are in continuous evolution

                                                                 Article : From perlong medical (
www.pl999.net)

New method of conquering adrenal artery embolization by automatic biochemistry analyzer

Adrenal artery embolization is difficult to cure, for this difficulty, experts and scholars do a series of clinical testing by automatic biochemistry analyzers, constantly exploring a new treatment of trigger aldosteronism,.
    Many problems of existing treatments Aldosterone adenomas or most of the unilateral adrenal hyperplasia cured by surgery, the rate was 80%; Idiopathic aldosteronism operation effect is poor, only about 30% efficient; And surgical trauma is big, there are some serious complications. Clinical common spironolactone primary aldosteronism, although effective but side-effect apparent. For this reason, clinical has been exploring efficient, minimally invasive and less complications, the length of time is short, low cost method. CT or ultrasound positioning with percutaneous puncture adrenal lesions side, to inject inside adenoma is no water in the method of ethanol cases may make adenoma necrosis, but in this method according to the distribution is not ethanol in blood vessels diffusion, may make part of tissue and easy relapse.

    Percutaneous selective adrenal artery embolization (no water ethanol) method according to completely adenoma blood vessels distribution embolism, foreign research report success rate of more than 82%. This method choose ethanol as embolism reagent and use this method, they consider up, middle and under the 3 kinds of artery blood supply, proximal embolism form easily after collateral circulation. Ethanol can have been into the organization endings, totally destroyed endothelial structure, the real guarantee embolism parts organization death.

    Our experience on March 24, 2010, the first of aldosterone adrenal adenoma percutaneous selective artery embolization, and then try to idiopathic adrenal hyperplasia of selective embolization in our conutry. Up to now, our hospital has completed 10 cases, except one cases of anatomical structure abnormal (artery diameter of less than 1 mm), the godet cannot normal into outside, the rest 9 cases have been successful, is currently only in 1 relapse, the rest 8 cases of symptoms disappear completely.

2012年2月27日星期一

Information of Hematology Analyzer

Hematology analyzer, also known as blood cell analyzer, blood cell counter. This machine is widely used at all levels of hospital in China as well as around the world. It not only improves the accuracy of the experimental results, but also provides a number of experimental indexes, which play an important role in the diagnosis and differential diagnosis of the disease.

    The hematology analyzer is a very wide range of hospital clinical laboratory instruments. The blood test blood means the common test of blood counted under the microscope, which includes red blood cells, hemoglobin, white blood cell count and its classification, platelet count, a total of 10 to projects. A patient's blood test is the most skilled, the most rapid at least 10 minutes. With the rapid development of science and technology, the automated hematology analyzer, blood cell analysis technology has changed from three sorts to five sorts since these years, and turned to the three-dimensional space from two-dimensional space, while the modern blood cell analyzers and five classification techniques use many advanced technology, such as the sheath flow technology, laser technology.

    In 1947, U.S. scientists Coulter (W.H.Coulter) invented the patented technology to count particles using a resistor. 1956 he successful applied this technology into blood cell count, the principle according to the non-conductive nature of the blood cells, blood cells suspended in the electrolyte solution to detect the resistance change caused by counting the holes, the blood count and volume determination, this method is called the resistance method or principle of Coulter. In 1962, the first blood count analyzer successfully developed in Shanghai. To the 1960s, the blood cell analyzer not only can count the blood cell, but also simultaneous determination of the HGB hemoglobin. In the 1970s, the platelet count instrument. In the 1980s, developed a classification of leukocytes (Category 3 and Category 5). In the 1990s, developed a blood cell count of red blood cells on the mesh analyzer, while five classification and the detection of immature cells are more mature and developing into blood cells analysis pipeline.
                                                                               Article : From Perlong medical (www.pl999.net)

Microplate enzymes : application of immune determination

Enzyme which is of microplate reader were used for drug and immune mainly small molecules detection ELISA is much more widely used, and it can be used to test the project includes the following respects.

1.Pathogen and its antibodies are widely used in the diagnosis of infectious virus hepatitis virus rubella virus herpes virus rotavirus, etc.; Mycobacterium tuberculosis bacteria, such as the streptococcus helicobacter pylori and brinell coli, etc.; Parasites such as day 2 amebic plasmodium falciparum, etc.

2.Protein molecule components of immunoglobulin tumor markers (such as a child protein carcinoma antigen embryo prostate specific antigen, etc) all sorts of plasma protein isozymes (such as creatine kinase CK-MB) hormone (such as hCG FSH TSH).

The peptide hormones such as T3 T4 estrogen cortisol, etc

4. Drugs and drugs such as digoxin benzene benzodiazepines gentamycin morphine and so on

Enzyme immunoassays are highly sensitivity and specificity, almost all of the soluble antigen antibody system to detect it can all be the smallest testable value can reach ng pg level and even ria than analysis, the enzyme is the advantage of immune determination mark reagents is stable, and there is no harm radioactive, therefore, the application of the enzyme immunoassays changes with each new day, the enzyme immune new method for the determination of the new technology development but enzyme immunoassays in medical inspection in popular due to commodity kit and automatic or semi-automatic testing instrument the appearance of the enzyme were immune complex step, reagent preparation is only with difficulty to meet the requirements of reagent and standardized operation, can obtain satisfactory results

Commodity ELISA kit should include bag was good solid phase carrier enzyme combined substrates and twist and other advanced kit not only provide all reagent ingredients, and all are made into reagents application liquid, and in all kinds of reagent to add pigment, make present different color ELISA procedures, reagents used is much also, this is a convenient operation and non-ferrous reagent to reduce operating error ELISA all except to quantitatively measure instrument need in the excellent instrument (special called ELISA read the instrument) outside, washing board is also extremely useful washing machine using not only save time save work, but also to standardized operation, to small and medium-sized laboratory is practical and accessible but should pay attention to in using
microplate washer before, should be first to wash the performance of the machine to check, confirm the hole cleaning effect is thoroughly, and repeat it well.

Semi-automatic and
automation ELISA analyzer also is mature, and in the large and medium-sized clinical inspection laboratory automation ELISA analyzer has application has an open system (open system) and closed system (close system) two classes of the former is applicable to all 96 hole plate ELISA determination; The latter only and supporting the use of specific reagents
Immune filtration test and immune chromatography test is a simple fast single testing results of many advantages, such as no equipments, instruments, reagent stable, so much of this kind of test for emergency inspection not accurate quantitative, so mainly limited to test the normal body fluids not the substance (such as the diagnosis of infectious diseases or antigen antibody), and normal and very low content in a special case abnormal rising material (such as hCG) currently clinical inspection has carried out a project hCG of HCV and HIV, HBsAg etc, new projects are in continuous evolution

                                                                 Article : From perlong medical (
www.pl999.net)

Change the biochemistry analyzer test parameters

Biochemical analyzer test parameters changes in the sample is more than reagents, and in what circumstances to change than sample reagent? The instrumentation equipment and reagents manufacturers have differences, so for a given sample reagent reagent manufacturers than does not necessarily ensure clinical analysis and reliable.
      Restrict samples than many factors of reagent, in addition to the reaction, the first to be biochemical analysis and sample system restriction, can appear sometimes given sample reagent and instrument than not sample system within the scope of the samples than reagents (mainly some centrifugal biochemistry analyzer), therefore needs to be changed. Then under the restriction of the photoelectric detector biochemical analyzer, sometimes in normal test, absorbency range will more than photoelectric detector linear range.
      So if we can change at will? Obviously is no good, sample reagent changes than by many factors limit.
1. The restriction by measuring method. Because change than sample reagents, can actually as concentrate or dilute the sample, so is likely to test range, so change samples than and take account of reagent detection limit. Also, sometimes more than detection range of the specimen also through change sample to concentrate or diluted reagent board of purpose.
2. Linear restriction by photoelectric detector. Because all sorts of analysis instrument of linear photoelectric detectors on the range, and when the change after samples than reagents, cause spectrophotometry is beyond the scope of linear area, cause error, so must consider analysis instrument photoelectric detector of linear range. Instead, for normal verification spectrophotometry is beyond the linear, also should consider adjusting samples than or replace reagent reagents.
3. The photoelectric detector by the restriction of the resolution. Is an important index of photoelectric detector, some optoelectronic detector resolution of 0.0001 Abs, and some only 0.001 Abs, determination coefficient for large and photoelectric detector resolution hours should intensify samples than to reduce reagent photoelectric detector error of the resolution. Also, in reducing reagent when sample than must also consider the resolution of the photoelectric detector error influence.
4. Lang "by the restriction of the beer's law.
Biochemistry analyser is based on a long the basis of beer's law ", and lang "bill law established a a premise, is rare solution. Because only in a dilute solution to ignore the molecular interactions, such spectrophotometry and concentration proportion to existing relationship, so in change sample reagent than, can't unlimited change.
      All in all, only in recognizing various relations to know to don't change, can change and how to change.

Article : From Perlong medical (www.pl999.net)

2012年2月26日星期日

Application of Blood coagulation analyzer

Advanced medical equipment company production equipment in the hospital diagnosis and treatment is playing a more and more important role, along with blood clots conventional check into the automatic analysis time automatic blood clots analyzer for the application of the thrombus hemorrhagic diseases and before the treatment of thrombosis state prognosis analysis provides more actual indicators, the instrument of the detection speed, ensure the reliability and accuracy of the test results, the use of good blood clotting and instrument normal operation, has become a medical work related to ensure operation conditions.
We depend on
blood coagulation analyzer the use of the instrument should be pay attention to during mention some fellow views for the reference.

Collection and save of sample
1.1 The test specimen avoid blood fat happened, fasting blood for good, otherwise, it will influence the results, the process of blood had better not firm a tourniquet or try to firm pressure with small, short time, the smooth of blood, or a small clot and small sample redfiliform jams needle, affects the test results can't in passive congestion or was put on a drip take blood in the needle, don't beat blood parts, lest cause hemolytic ZuZhiYe mingling with the bubbles.
1.2 Anticoagulation with 109 mmol/L [1] concentration, according to the proportion of anticoagulation and blood now.
1.3 Test tube with the plastic pipe or the request of the glass tube carried the best specimens in one hour centrifugal separation plasma, four hours after the plug determination and don't open centrifugal, because can prevent CO2 to escape, change PH value can make the PT APTT results such as the extension with speed 2500 r/min centrifugal 10 ~ 15 min, or red blood cell plasma interference is determined.
2. Analysis
First instrument to install in no vibration stability strong mesa, dustproof moistureproof with good ventilation in the environment.
2.1 test reaction cup to clean, one-time glass and plastic products more suitable for this experiment, or join will have bubbles influence after reagent colorimetric determination
2.2 Reagents containers and reagents don't put it on the apparatus, add reagent and instrument remove after put back, lest meet pour container and a reagent pollution instruments; Can't work while add reagent, to meet the required amount of determination, add reagent a add the, lest appear insufficient reagents and call the police phenomenon.
2.3 The use of the reagents should strictly according to the requirements of the reagents into limit, placed longer time will affect the accuracy of the determination results.
2.4 The determination to use clean liquid flush, remove the needle probe wall attachment protein, ensure the smooth wall two needles, no congestion, ensure that add kind not pollution reagent reagent needle.



                                                                                                 Article : From perlong medical(www.pl999.net)



How to clean the biochemical analyzer pipe


Automatic biochemistry analyzer in daily use, often encounter pipeline plugging, lead to the instrument of the normal operation of the following is not of the instrument pipe cleaning is introduced .

Beckma model 700 semi-automatic biochemical analyzer pipeline cleaning: this kind of instrument of single directly, from the real to the measurement of the suction pool export pipeline, can be the reaction liquid pollution, long-term protein precipitation, leading to increased blank spectrophotometry is right now but will 84 disinfect 4 to 1 add water dilute ratio, directly from smoking are sucked into 2-3 times, for 2-3 minutes and then rinse with distilled water and dozens of times, moves to A 340 nm wavelengths, blank A recover soon to 0.0010 below

2. Vitalab200 biochemistry analyzer pipe cleaning; This instrument pipe is continuous, than color by artificial clean cup although can wash, but due to pipe reaction of residual liquid dirt sedimentated to use 84 disinfection 1 8 diluted by smoking distilled water pipe, with the main directory blunt washing procedure 2, 3-4 times flush, immerse 2-3 minutes, put straw then insert bottles, rinse again about 40 times, you will see the dirt eliminate, row to water bottle, along with the water into steam slipped, pipe gradually clean

3. DH501 potassium sodium instrument pipe cleaning: this instrument has two handle, one is flush pump, the other is a sample of the pump suction pump operation can wash rinses (factory equipped with) infiltrating each measuring pool and saturated and than electrode, the other a suction pump suction of the samples are measured serum row off work at ordinary times, serum levels of inhaled, easy to measure pool and the entire pipeline pollution macroscopic observation pipeline cloudy fuzzy, use 1 8 diluted 84 disinfection let wash pump operation directly several times, then visible pipeline and measuring pool gradually clear transparent real will suck after removal of the syringe inhaled with dilute flush, the effect also obviously two pipe after rinse clean, to replace the electrode, garnish with manufacturer of rinses stability with certain time, they can be used for measurement

4. Summary: use the rinses, soaking time cannot too long, usually two to three minutes, as soon as possible after soaking with distilled water to rinse clean, no residual rinses, otherwise you will pollution pipe, effect on the determination by our years of practical application, this rinses effect is especially good, can be applied


                                                           Article : From perlong medical (
www.pl999.net)

How to maintain the biochemistry analyzer

Recently, the purchase of our medical device company by the production of biochemical analyzer always appear problem, on test results, although and medical equipment company after contacts have to solve the problem, but in case the similar problems, summarize the following a few simple maintenance and maintenance skills.
      A. The daily maintenance
(1). Before starting :
1. To examine two cleaning trough 1 D1, 2 of the liquid will be enough for Hitergent D1 amount.
2. Check the small sample trays W1 a 2% Hitergent whether fluid enough quantity.
3. To examine two pack cleaning reaction cup of cleaning in the bucket washing liquid and 0.1 2% Hitergent mmol/L HCl is enough quantity.
4. Check printing paper.
(2). After startup:
1. The executive photometric inspection.
2. Check and additive reagents.
(3). The phone was off:
1. With no water alcohol from up to down carefully wipe the tip and stir bar, in polished stir bar don't damage when its surface hydrophobic material.
2. Empty waste liquid barrels.
3. If the sample slot have dirt, gauze to wipe.
2. Weekly maintenance and maintenance
1. In two cleaning trough 1 D1, 2 D1 a 2% change Hitergent liquid, and the implementation of the "Wash Cells".
2. Blank and print data determination cup, requirement as follows:
(1). 1, the value of the cup reaction not greater than 16000;
(2). 2, 160, the value of the cup in + 800 range.

      3. Cleaning reaction cup:
If the execution "Wash Cells", a cup of blank do not meet above requirement, the reaction cup soaked in 2% Hitergent out in the fluid of more than 2 hours, use a swab to wipe, and pure water flushing, fully Wash clean install, and then execute a cup was blank.
3. Monthly maintenance and maintenance
1. Cleaning three screen:
(1). The shrinkage filter pressure machine;
(2). The service entrance screen;
(3). The reaction tank drain screen pack.
2. Two cleaning system:
(1). Cleaning suck the needle, needle and sample reagent stir bar washing the pool and pipe:
A. flush with wet with the brush pool tube 2% Hitergent liquid brush net;
B. first 10 ml 5% sodium hypochlorite liquid injection pipe flushing eduction, garnish with pure water flushing 3-4 times.
(2). A cup of cleaning system no. 1 needle: at boot status, the no. 1 needle, take it out of a small beaker filled with 5% sodium hypochlorite liquid, with the hand to control the needle with other needle as synchronous movement up and down.
3. A reaction tank:
(1). The reaction tank discharge water:
A. with injector spare water trough;
B. or executive "Inc. Water Exchange" (when the response of the Water tank when shutdown at once).
(2). With gauze with 2% Hitergent liquid cleaner reaction tank;
(3). Use a swab with 2% Hitergent liquid wipe two pervious to light window.

4. Every quarter maintenance
1. Change than color cup: in practical application replaced every six months, depending on the specific cup blank and decide, when a cup of blank is not accord with the general proceed as follows operation:
(1). In two cleaning trough 1 D1, 2 D1 a 2% change Hitergent liquid, and the implementation of the "Wash Cells".
(2). Take the reaction cup cleaning;
(3). The reaction tank cleaning;
(4). Put on a new light bulb;
(5). Put on a new has set up a file in Hitergent soak overnight in the fluid of 2% with pure water thoroughly clean the cup after reaction.
2. Replace sample syringe gasket;
3. Copy, replacement system disk and data plate.
Five. Every half year maintenance and maintenance
1. Replace light: (as long as have the following circumstances)
(1). Executive photometric inspection, if absorbency value beyond 16000, eliminating reaction cup and reaction tank pollution situation, should be to change;
(2). Light use time more than 750 hours, should be replaced.
2. Cleaning floppy disk drive;
3. Replace mechanical butter: first use gauze to wipe away the sample needle, needle, plus sample reagent stem butter, again with gauze daub the fresh butter.


Article : From Perlong medical ( http://www.pl999.net/)

2012年2月23日星期四

FIA8000 Immunoassay Analyzer——Fast and accurate POCT quantitative detection system

According to not complete count, global each year about 15 million people die of a heart attack all over the world.China each year about 3 million people die of cardiovascular disease, accounting for 20% of the global death rate from heart disease. And heart attack patients before the onset of the general no special obvious signs, the fast, and a high mortality rate. Heart disease is serious threat to human health, so the diagnosis and treatment time will be particularly important to heart patients. At present, Perlong Medical launched a prompt and the rapid detection of FIA8000 Immunoassay Analyzer, fast and accurate POCT quantitative detection system
    FIA8000 Immunoassay Analyzer, fast and accurate POCT quantitative detection system has the function of small, portable, automatic test, automatic printing and the operation is more simple. The analyzer can store 5000 ~ 10000 of testing data and can test at any time .The sample is serum, plasma or all the drops of blood to detect. The time of the result is in10 or 20 minutes and short the cycle time, save more time of the patient.According to international standard quality control, product quality is stable and reliable, and can be at ease use.
   FIA8000 Immunoassay Analyzer test items cardiac troponin test kit, N-end brain natriuretic peptide precursor detection kit, N-end brain natriuretic peptide forbody/myocardial for troponin test kit furniture (global starting), creatine kinase isozyme/cardiac muscle calcium protein/muscle protein detection kit, red one gao min c-reactive protein detection kit, the d-dimer test kit, more comprehensive testing heart problems.It is convenient for doctor to make rapid diagnosis treatment.
  Application field is also widely: heart medicine, emergency service and the clinical laboratory, clinics, ward, operating room, ICU, CCU and oncology, renal medicine, endocrine division, and pediatrics, old age section, chest surgery and so on. According to the current market conditions, FIA8000 Immunoassay Analyzer, fast and accurate POCT quantitative detection system is accurate, rapid, convenient and so on. Doctors, patients need bed timely detector. The good is  trustworthy!
                                                                   Article : From Perlong medical (http://www.pl999.net/)

Why do hospitals need advanced radiography machine ?

Good radiography machine  has good photography and can help doctors found lesions early.Early treatment can serve the clinical better.

    What's the meaning of the hospital introducing radiography machine ?
     Improve the competitiveness of the hospital in the medical market.
    1, X-ray always is the general hospital of traditional necessary departments.Radiography machine,medical X-ray machine and so on has been the most commonly used  in radiologists medical equipment. Hospitals whether physical or scan can not leave
radiography machine. Advanced radiography machine has good photography and can help doctors found lesions,make the accurate plan of diagnosis. Along with the development of medical field in radiology, radiography machine is becoming more and more irreplaceable, good advanced radiography machine also affected by the hospital.
    2, Provide the good clinical fast diagnosis
    The advanced radiography machine can take out clear, exquisite, high-contrast images and reduce the omission of lesions.It can help the doctor to accurate diagnosis of  the  disease, especially the discovery of early lesion .

    3,Provide needs of comprehensive inspection from clinical project 
     At all levels of hospitals,it used to take photography of human body, head, chest, abdomen, lumbar, limbs parts of lie/common /side.It also has some piece of photography   and high kv photography.It is matching with vertical photo frame and can be used for routine head, chest, abdomen, pelvic, spine and surrounding endings check photography. It also can be used with all kinds of CR use.
     What kind of radiography machine is in line with our requirements?
     It is installed with close-table graphical colorful LCD touch screen, wireless remote control exposure, make the operator easy to use.

About Blood gas electrolyte analyzer

Blood gas electrolyte analyzer is a kind of medical equipments to test blood and has the advantages of quick testing , convenient, range, etc. It can not only to detect the patient in the blood of the oxygen and carbon dioxide gas content and blood acid-base value and relevant index changes in a few minutes and also can rapid response blood potassium, sodium, calcium content, for those who in the salvage rapid and accurate detection provides favorable safeguard.From these, we can see the Blood gas electrolyte analyzer is very important. But it is very difficult to medical equipment manufacturers from China to develop the quick, convenient, without the cylinder and calibration liquid in the  Blood gas electrolyte analyzer.Now, some hospitals from China are used the analyzers from foreign .But the overseas import products have some shortcomings, cost also will be high. To this situation many and many hospitals are also helpless.

  
Blood gas electrolyte analyzer
   In order to solve these difficulties now domestic appear, Perlong Medical researches and will be coming PL2100 Blood gas electrolyte analyzer. The Blood gas electrolyte analyzer use measuring technology of solid-state ion selective electrode sensors.The blood samples will not use centrifugal.The blood gas electrolyte can do measurement of whole blood directly .The contains of the serum have sodium, calcium, potassium and chlorine ion concentration, PH value and carbon dioxide.This blood gas electrolyte analyzer has these features :free maintenance, loading and unloading convenient, measurement is stable and reliable,  big screen display, automatic screen saver and convenient operation.The users can  the demand according to oneself choose electrode channel by themselves according to their demands. And it can reduce reagent consumption and save maintenance cost.

   Perlong Medical adhering to concept of development "Cherish Your Life and Care About Your Health" .And we will continue to launch new products, provide more convenient to  the partners, also hope that the new and old partners can give us more suggestions.
                                      

                                                        Article : From Perlong medical (http://www.pl999.net/)

2012年2月22日星期三

Experience of using urine analyzer

In 80s,urine analyzer is researched and developed by medical equipment companies. Due to its simple operation, quick, it has become a necessary equipment for hospitals . But how to ensure the accuracy of the test results and the reliability is not easy. From all around pharmacological basis every laboratory and daily control situation, the differences between each instrument is unsatisfactory, sometimes even as visual result is accurate, and even misdiagnosis. Investigate its reason, mainly because the use method and maintain is not ture. We summarize the experience of using it for 10 years .And list them for reference.

      1 Perfect management system is to guarantee the normal operation of the instrument.

      1.1  Urine analyzer is a basic laboratory equipment, use frequency is high and the workload is big, each staff should grasp skilled. So the necessary to use the management system and the operation manuals, used the recording, fault and maintenance records must be set up. To carry out routine maintenance, fault rate will inevitably less, the fault analysis and maintenance also convenient, at ordinary times working quality is guaranteed, that every staff uses urine analyzer easily.They do every day with the test standards, every week do artificial urine qc, for many years in addition to updating the accessories has been using normal, get the clinician's widely sure.

     1.2  Work environment must follow the manufacturer requirements. Such as voltage should be stable in 220 + 10 V between, or should add regulators; Indoor clean; Relative humidity below 50%, or integral ball easily pollution of aging. Indoor temperature relatively stable, try to stability in the 18-28 degrees between. Low temperature of the chemical reaction is slow, the result is low, the temperature too high chemical reaction too fast, false-positive rate increases.

     1.3  The quality of the dipsticks affected the accuracy of the test reults. We have in the same instrument with five domestic 8 A dipsticks to the same quality of urine are measured, and the results urine 1 + 3 +, PH4.5-6.0, protein 1 + 3 +, concealed blood 1 + 3 +, bilirubin 0-2 +, ketone bodies 2 +-4 +. Show that dipsticks from different manufacturers have different quality , so preparation or purchase artificial urine to conduct regular indoor qc testing of dipsticks is very necessary. At the same time that the nation in control diagnostic reagents in market access should be strengthened.
     2 Regular maintenance can ensure is the normal work of the instrument
     We usually do the comprehensive clean for one month, every three months for a complete overhaul, including a complete clean and integral ball light value determination.The method is turned on hold and the key to START UP key, turned on the power and into the standard tests with a test.The instrument can be printed out 620, 550 light wave length value, general should be controlled in 1500-2000, more than the range can be adjusted three integral ball potentiometer, if not reach the 1000 show that integral ball is old and must be replaced. Another light path components to keep clean, light lamp wants to change regularly to ensure that the light value meet detection requirements.

      3  Carefully analyse the reason of failures and promptly eliminate

     3.1 TROUBLE-4: is the most common fault hint, show that light value shortage,  the failure may cause by these reason:

      3.1.1 Illuminant light bulb aging or inappropriate position, to try again after replacement bulbs, especially on counting window should be the filament.
      3.1.2 Light path has dirt, and check the dirt and mass of detect windows, reflex, slice and optical path.
      3.1.3 After replacing bulbs should reduced the voltage of both ends of the light source
      3.1.4 Point light source for deviation, after startup observation points under the ball out of the window as if light with reagents base corresponding article, or should be adjusted integral ball position.
      3.1.5 Integral ball of the window seal off, vapor evaporation to speed up the ball inside the integral points of aging, should resume will seal piece of cement.
      3.1.6 Article reagent base pollution, poor drainage, or partial a also can cause the above suggestion.
      3.1.7 Above check is normal, failure can't rule out, may be integral ball aging, but by measuring the integral ball light value to judge.

       3.2 TROUBLE-5: Common reason is placed inappropriate position of article reagent or article reagent base two detection hole pollution, the cleaning can, another integral ball aging also can appear above tip.

       3.3 Print chromaticity abate, not clear, for printed piece of aging, general is updated annually

       3.4 Print or don't walk deviation of paper, printing gear damage, should be updated gear

       3.5 Urine pump sucks fluid ability is not strong, should check whether the pipeline leak jams, liquid bottle mouth sealing lax, if pipeline problem solving, should check whether the urine pump gateway jam and, when necessary, open pump to examine two negative pressure membrane is damaged, update when necessary.
      The operation of urine analyzer is fast and simple and the machine has a high degree of automation.But because it is the most frequent use, working time the longest, application scope is the most extensive use, so the relatively high failure rate, the cause of failure is various, but maintenance is the key.Only when we do well in the day-to-day management of the instrument, regular maintenance, timely to ensure out fault the normal operation of the instrument. In addition it is after all a half quantitative instruments, human urine concentration is unable to control, timely communication with clinical and, when necessary, do the biochemical quantitative diagnosis in urine.
                                           Article : From Perlong medical (www.pl999.net)

Pay attention of using urine analyzers

Urine analyzer is made by the reflection, the microcomputer and printer photometric type and the machine suitable and other components of the test of urine. To detect the urine eight or 10, 11 of urine. In this paper, the medical equipment company production of urine chemical analyzer use should be paid attention in the common problems summarized as follows:

   Firstly should be clear : urine analyzer test is only a screening test, firmly opposed some units use urine after chemical analyzer will no longer be microscopic urine dreg wrong tendency. Some units will no longer quote urine color, transparency and general properties check, this is wrong. Many institutions will thermal papers report directly to stick on the list in practice is wrong, for thermal papers report on the handwriting encounter heat or a few years will resolve, not as file save.

   1 Operators must be carefully before taking up their jobs to reading the instruments instruction and know the determination of instrument principle, operating rules, calibration methods and the instrument maintenance requirements.

  2 Must understand the film with the test of reaction mechanism, the points for attention and the drugs can appear abnormal of interference and reference range. Part of the instrument on though it automatic correction, but still should insist every day will instrument with the correction of random with calibration, measured results and correction marked with the result is consistent, only to prove the device is the same in normal operation condition. Must do record carefully.

  3 Use  "normal" and "abnormal" two concentration quality content for testing every day. If "normal" that control the results into abnormalities, or "abnormal" thing to control the normal to failure are results, should stop detection of patients with specimens, looking for reason. If a piece of quality content in a target value degree is obtai within a level, still as out of control to punish. Above content test results shall control the detailed record.

  4  Urine specimen must be fresh, and according to requirements enrol your biometrics. From the eduction to testing should be done in 2 hours, otherwise, it will affect urine chemical components and visible part, such as not timely inspection or analysis.And it should sotre under 4 ℃ , but the longest time of cold storage must not exceed 6 hours. Sometimes some cold storage which will impact the crystallization. From out of the refrigerator urine sample should be placed in a certain amount of time at room temperature, make urine specimen to room temperature constant temperature flat after mixing outright, and then testing samples.

   5 Urine test belt should be according to the manufacturer's recommended preservation conditions and use in the effective period. Should not try to take on under the direct light or exposed to radiation in damp environment. Once the required amount of try take only with, and shall be immediately put the cap. Try extra with may not be returned to the original container, more should not be each bottle of merger with try. Operation: do not touch the try take attention reaction monitoring of film.

   6 To pay attention to try drugs with determination of interference. Especially vitamin C can make the urine, bilirubin and uric bravery former is false negative. To avoid the effect of the vitamin C, can choose the fight vitamin C with or try with the vitamin C film piece of color try belt. The current domestic urine test have not agreed with the quality standards, so that it can cause the result differences, therefore do not easily replace different manufacturers try belt.

   7 To pay attention to urine analyzer with manual measuring results of chemical method of the differences. For example the urine test with determination is of albumin, but not sensitive to globulin; With the sensitivity of urine glucose oxidase determination than class's method is high, but high concentration measure only 3 +; Uric bilirubin try take the result is better than harrison craft law sensitivity low; Check whether can only detect urine white blood cells called, but not with lymphocytes reaction, etc, please refer to the related reports in the literature.
                                                               Article : From Perlong medical (www.pl999.net)

What are c arms?

An imaging scanner intensifier, so named because of its configuration. C-arms have radiographic capabilities, though they are used primarily for fluoroscopic imaging during surgical, orthopedic, critical care, and emergency care procedures.

    C-arms are one of the driving technological forces behind the advancement of minimally invasive surgeries. These mobile fluoroscopic imaging systems are precise and accurate devices that allow for less patient discomfort in a variety of surgical and nonsurgical procedures. The minimal invasiveness with the use of C-arms has helped lead to the increase of more cost-effective outpatient care. C-arms provide patients with minimally invasive, pain-reduced procedures.

   Initially used in general surgery or orthopedic applications, C-arms are now described by both manufacturers and users as highly versatile, thanks to the technological advancements made since the original designs. In fact, C-arm usage recently has expanded to include minimally invasive, spinal, general, and orthopedic surgeries; pain management; and cardiac, urology, vascular, and neurovascular applications.

     An X-ray image intensifier (XRII), sometimes called a C-Arm, refers to a special image intensifier device used in medical imaging involving x rays. It consists of an input window, input phosphor, photocathode, vacuum and electron optics, output phosphor and output window. It allows for lower x-ray doses to be used on patients by magnifying the intensity produced in the output image, enabling the viewer to easily see the structure of the object being imaged. C-Arms were introduced by Philips in 1955.

   C-arm fluoroscopes seem to have increased in popularity over the past few years. Is personnel monitoring necessary when C-arms are used?

    Yes. Many C-arms users are unaware of the potential for high exposures from using this equipment. In general, the ways in which the construction and use of C-arms affect exposure levels have not been fully appreciated. Many users are not being properly monitored; without adequate personnel monitors, exposure from daily use of equipment cannot be accurately evaluated.

2012年2月21日星期二

S1100 Ventilator

Usage of ventilator
S1100 is  the type of electrically and pneumatically controlled synchronous respirator with time switch. It is mainly used for the saving of patients with respiratory failure field surgical operation and resuscitation after surgical operation. It can be used in the ambulance transportation and surgical operation outside, respiration medicine and operation rooms of various types of hospitals.



Feature of ventilator
1.Apply to adults and children

2.High intelligent control system

3.Multiple modes of ventilation

4.Double trigger function: IPAP and flow

5.Compliance compensation function

6.Colorful  LCD display screen , display alarming information and graphics ventilation parameters

7.Adapting item: air compressor and the function of grain and atomization

The brand of the  Ventilator is Perlong Medical.

Introduction of auto microplate reader : how much is microplate reader ?



Microplate reader in the hospital with general standard instrument in clinical inspection, and in daily use , it can use in a hospital outside, in the large feed mills place such as dairy food factory and so on ! In general,microplate reader can detect melamine milk powder in the content of fruit or vegetables can detect the residual pesticides in the AIDS virus and so on , so the use of microplate reader is very extensive laboratory class of medical apparatus and instruments.
            
Microplate reader in perlong medical, its technology are mature, the customer is also widely at home and abroad, the market share is also high to everybody below simply
introduce the enzyme standard instrument of knowledge .
Microplate reader is mainly used in hospitals and related experiments of enzyme league of immunology department detection work, the elisa experiments hematology immunology tumor immunology infectious disease immunology eugenic and superior nurture (TORCH infection) serological and gene experiment, animal medicine residual pesticide residues residual food allergen antibiotics melamine and so on many kinds of project detection.
Main application: U V type of a 96 holes and 48 hole enzymes panels

Feature of mciroplate reader:
1.Instrument measured accurately, repeatability, with QC function, and can do spectrophotometry is qualitative and quantitative detection.
2.The instrument has the boot self-check function and communication function.
3.The instrument can be connected to the computer and software, can do personal tracking report comprehensive report statistics report cut in data etc. function.
4.Instrument filter standard configuration has 4 pieces: 405 nm 450 nm 492 nm 630 nm,
most can match 10 filters, the most of the imports can be equipped with eight.
5.Read board speed: single wavelength < 5 seconds / 96 hole, double wavelengths < 7
seconds / 96 hole six instruments both at home and abroad, to open, reagent manufacturers reagents.
The above is the performance characteristics of four of microplate reader in perlong medical , for your reference.

                                                                           Article : From perlong medical (www.pl999.net)

2012年2月20日星期一

How much is the medical diagnosis X-ray machine?

Along with the development of medical technology and progress, medical diagnosis X-ray machine has been used widely in the hospital of the various departments, such as involved in families, orthopedics, pain families, oncology, gynecology, urology cardiology department, and so on. For medical diagnosis X-ray machine can no and to the human body parts to the injury or disease structure for inspection, still become a indispensable medical equipment.
Perlong company-PLD6800 not only has beautiful shape, also has more powerful performance advantage: this machine can be used for gastrointestinal perspective/photography, gut check, chest photography, head and systemic skeleton photography, mri, esophagus gastrointestinal, mri, spinal cord angiography, joint space imaging, bile duct, mri, bronchial imaging, vein, mri, peripheral angiography, urinary tract, mri, uterus, fallopian tube imaging pediatric imaging, raditherapy for application and so on.
And the company consists of a number of the company consists of a number of years in medical digital X-ray machine research technique of elite, and now has successfully launched gastrointestinal machine, 500 mA shooting machine, 
electric catheter bed and a series of products, the products have passed the provincial and national product registration certificate and gained national mandatory product certification "3 C" certificate. On this basis, the company sets up the digital X-ray machine more than laboratory, specializes in digital X-ray machine development, both in hardware and software made a major breakthrough, the rapid development for the company, and laid a solid foundation.
PLD6800 high frequency digital multi-function medical diagnosis X-ray machine was zhuhai's newly launched at present the most advanced digital gastrointestinal machine, which has one of the humanized design and the advanced technology level,
 all without exception is praise.
So, how is medical diagnosis X-ray machine the work, and how should we choose a high quality, suitable for their own medical diagnosis X-ray machine?
Medical diagnosis X-ray machine Lord if produces x-rays of the tube, collect the image of the image intensifier and CCD camera, and image processing of the workstations. Mainly used for various operation, mri, point the perspective of work, etc.
So medical diagnosis X-ray machine brand so much, how should we choose? Or domestic medical X-ray machine price what is the interval, medical diagnosis X-ray machine probably how many money a?
First of all, imported brand, the price is too high; Large hospital also can take on, but small hospital or medical agency estimates that it's difficult to get up. As a years of use X-ray machine for the doctor, I personally think domestic products both in technology, function and quality are very advanced, also can meet the need of our daily work. And the price is also is higher, very suitable for domestic 
hospital buying used.

The application of microplate analyzer in the ELISA

In elisa testmicroplate panels for the cleaning work more and more high, in order to effectively reduce the cross contamination, to ensure the accuracy of the test results, microplate has become elisa test 
microplate panels of professional cleaning for medical equipment and microplate 
necessary use standard analyzer. Make its elisa test to be more perfect.
Perlong medical as microplate specialized production factory, the application on the most advanced international no positive negative pressure technology latest a diamond level of high-grade new computer microplate . Its technology to achieve domestic industry series of medical equipment is the most advanced level. In the original basis, increased the liquid level detection alarm device, 
liquid bottle, lotions bottle and distillation bottle liquid surface alarm, can choose any. Microplate analyzer united inspection in the main functions is used to remove in ELISA reaction of the existence of the 
distraction material, already ensure the accuracy of the test results. In addition, microplate in after work, must clean way of liquid, prevent stranded in long-term catheter twist, happen crystal chromatography phenomenon, lead to pipe pollution and needle tube jam, make note fluid amount not accurate, washing board quality drop, can't even work.
In the future, elisa test will be replaced by artificial microplate wash program that makes the enzyme league inspection the work more efficient ,accurate and perfect.