The first Blood Coagulation Analyzer was invented by Kottman in 1910, which to reflect the plasma solidification of time through the determination of blood clots viscosity changes.
So you may want to know what Blood Coagulation is. Coagulation is the process by which blood forms clots. It is an important part of hemostasis, the cessation of blood loss from a damaged vessel, wherein a damaged blood vessel wall is covered by a platelet and fibrin-containing clot to stop bleeding and begin repair of the damaged vessel. Disorders of coagulation can lead to an increased risk of bleeding (hemorrhage) or obstructive clotting (thrombosis). Coagulation is highly conserved throughout biology; in all mammals, coagulation involves both a cellular (platelet) and a protein (coagulation factor) component.The system in humans has been the most extensively researched and is therefore the best understood.
Coagulation begins almost instantly after an injury to the blood vessel has damaged the endothelium lining the vessel. Exposure of the blood to proteins such as tissue factor initiates changes to blood platelets and the plasma protein fibrinogen, a clotting factor. Platelets immediately form a plug at the site of injury; this is called primary hemostasis. Secondary hemostasis occurs simultaneously: Proteins in the blood plasma, called coagulation factors or clotting factors, respond in a complex cascade to form fibrin strands, which strengthen the platelet plug
After 70 s, due to mechanical the development of the electronic industry, make all types of automatic blood clots instrument has come out.
In the 80 s, because developing substrate method came out and was applied to the blood clots detection, make automatic Blood Coagulation not only can carry on the general screening tests outside, also can undertake blood coagulation anticoagulation fibrinolysis system single factor detection.
As a manufacturer, we delicate to develop more advanced machine well applied in the medical filed and do the best we can do to make contribution to the human society.
Article : From Perlong medical (http://www.pl999.net/)
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