Three of the rapid detection of myocardial infarction clinical significance

Perlong medical equipment company of acute myocardial infarction three rapid diagnosis refers to cardiac troponin I (CTnI), creatine kinase isozymes (CK-MB), muscle red protein (Myo). Mi the clinical significance of three fast detection are:

Muscle red protein (Myoglobin, Myo) : is the myocardial after damage happens unusual increase the earliest of the heart muscle protein markers, an acute myocardial infarction (AMI) attack after 2 h the serum Myo is beginning to rise, 4-6 h amount to a height. Due to Myo no myocardial specificity, muscle protein to rule out the red negative of AMI diagnosis; Use the markers the best strategy is to use its high negatie predictie alue and sensitivity to rule out myocardial infarction.

Myocardial CTnI (CTnI) : is currently accepted, specificity and highest longest diagnosis the reliability index of myocardial infarction. Cardiac muscle calcium protein in general myocardial injury four to eight hours after in the peripheral blood is higher, the highest in the 12 to 24 hours to appear. After myocardial injury in 7 to 10 days in peripheral blood still can be detected the increased cardiac troponin calcium protein. Acute XinGengBing people in the blood of the concentration can be as high as 100 cTnI-300 ng/ml. Mainly used for myocardial injury-especially for the diagnosis of small damage, it can also be used in heart surgery at the reliability index of myocardial ischemia, could be used to evaluate the myocardial protection measure. Acute myocardial infarction (ami) fibrinolytic therapy the pointer; Judge reperfusion effect.

CK-MB: is the clinical doctors most reliable AMI detection, specificity is higher.

In cardiac injury should be synchronous detection markers testing related markers. Three markers Myo, cTnI, CK-MB release time is different, and rapid determination of three markers, a determination alone more convenient, more rapid, on time synchronization is more advantageous to the analysis and judgment of the results, which can do more rapid, accurate diagnosis.

Article : From Perlong medical (http://www.pl999.net/)
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